All 2022 2021 2020 Basic research CNS Review article Guidelines Others Systematic review / Meta-analysis Pancreas Clinical research MPM Ovary Case report Pediatric Breast

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Genome-Wide Expression and Anti-Proliferative Effects of Electric Field Therapy on Pediatric and Adult Brain Tumors

2022 Basic research CNS
Branter J, Estevez-Cebrero M, Diksin M, Griffin M, et al. Int J Mol Sci. 2022 Feb 11;23(4):1982. Link [2022][Basic research][CNS]

PARP Inhibitors in Glioma: A Review of Therapeutic Opportunities

2022 Review article CNS
Sim HW, Galanis E, Khasraw M. Cancers (Basel). 2022 Feb 16;14(4):1003. Link [2022][Review article][CNS]

Tumor Treating Fields dually activate STING and AIM2 inflammasomes to induce adjuvant immunity in glioblastoma

2022 Basic research CNS
Chen D, Le SB, Hutchinson TE, Calinescu AA, et al. J Clin Invest. 2022 Feb 24:e149258. Link [2022][Basic research][CNS]

Congress of Neurological Surgeons systematic review and evidence-based guidelines update on the role of cytotoxic chemotherapy and other cytotoxic therapies in the management of progressive glioblastoma in adults

2022 Guidelines CNS
Germano IM, Ziu M, Wen P, Ormond DR, et al. J Neurooncol. 2022 Feb 23. Link [2022][Guidelines][CNS]

Clinical strategies to manage adult glioblastoma patients without MGMT hypermethylation

2022 Review article CNS
Liu D, Yang T, Ma W, Wang Y. J Cancer. 2022 Jan 1;13(1):354-363. Link [2022][Review article][CNS]

The Impact of Tumor Treating Fields on Glioblastoma Progression Patterns

2022 Basic research CNS
Glas M, Ballo MT, Bomzon Z, Urman N, et al. Int J Radiat Oncol Biol Phys. 2022 Apr 1;112(5):1269-1278. Link [2022][Basic research][CNS]

Therapy for Diffuse Astrocytic and Oligodendroglial Tumors in Adults: ASCO-SNO Guideline

2022 Guidelines CNS
Mohile NA, Messersmith H, Gatson NT, Hottinger AF, et al. J Clin Oncol. 2022 Feb 1;40(4):403-426. Link [2022][Guidelines][CNS]

Tumor treating fields: An emerging treatment modality for thoracic and abdominal cavity cancers

2022 Review article
Jones TH, Song JW, Abushahin L. Transl Oncol. 2022 Jan;15(1):101296. Link [2022][Review article]

DDRugging glioblastoma: understanding and targeting the DNA damage response to improve future therapies

2022 Review article CNS
Rominiyi O, Collis SJ. Mol Oncol. 2022 Jan;16(1):11-41. Link [2022][Review article][CNS]

Computational simulations establish a novel transducer array placement arrangement that extends delivery of therapeutic TTFields to the infratentorium of patients with brainstem gliomas

2021 Basic research CNS
Ramirez-Fort MK, Naveh A, McClelland S 3rd, Gilman CK, et al. Rep Pract Oncol Radiother. 2021 Dec 30;26(6):1045-1050. Link [2021][Basic research][CNS]

Health-Related Quality of Life for Patients Receiving Tumor Treating Fields for Glioblastoma

2021 Others CNS
Palmer JD, Chavez G, Furnback W, Chuang PY, et al. Front Oncol. 2021 Dec 2;11:772261. Link [2021][Others][CNS]

Tumor-Treating Fields: A fourth modality in cancer treatment, new practice updates

2021 Review article CNS
Arvind R, Chandana SR, Borad MJ, Pennington D, et al. Crit Rev Oncol Hematol. 2021 Dec;168:103535. Link [2021][Review article][CNS]

Glioma invasion along white matter tracts: A dilemma for neurosurgeons

2021 Systematic review / Meta-analysis CNS
Wang J, Yi L, Kang QM, Zhou J, et al. Cancer Lett. 2021 Nov 20;526:103-111. Link [2021][Systematic review / Meta-analysis][CNS]

Establishment of Tumor Treating Fields Combined With Mild Hyperthermia as Novel Supporting Therapy for Pancreatic Cancer.

2021 Basic research Pancreas
Bai L, Pfeifer T, Gross W, De La Torre C, et al. Front Oncol. 2021 Nov 3;11:738801. Link [2021][Basic research][Pancreas]

An overview on tumor treating fields (TTFields) technology as a new potential subsidiary biophysical treatment for COVID-19

2021 Review article CNS
Farmani AR, Mahdavinezhad F, Scagnolari C, Kouhestani M, et al. Drug Deliv Transl Res. 2021 Sep 20:1–11. Link [2021][Review article][CNS]

Study protocol for OptimalTTF-2: enhancing Tumor Treating Fields with skull remodeling surgery for first recurrence glioblastoma: a phase 2, multi-center, randomized, prospective, interventional trial

2021 Clinical research CNS
Mikic N, Poulsen FR, Kristoffersen KB, Laursen RJ, et al. BMC Cancer. 2021 Sep 9;21(1):1010. Link [2021][Clinical research][CNS]

Tumor Treating Fields (TTFields) downregulate the Fanconi Anemia-BRCA pathway and increase the efficacy of chemotherapy in malignant pleural mesothelioma preclinical models

2021 Basic research MPM
Mumblat H, Martinez-Conde A, Braten O, Munster M, et al. Lung Cancer. 2021 Oct;160:99-110. Link [2021][Basic research][MPM]

An insight into the risk factors of brain tumors and their therapeutic interventions

2021 Review article CNS
Rasheed S, Rehman K, Akash MSH. Biomed Pharmacother. 2021 Nov;143:112119. Link [2021][Review article][CNS]

Tumor Treating Fields for Ovarian Carcinoma: A Modeling Study

2021 Clinical research Ovary
Lok E, San P, White V, Liang O, et al. Adv Radiat Oncol. 2021 May 17;6(4):100716. Link [2021][Clinical research][Ovary]

Tumor treating fields combined with a poly (adenosine diphosphate-ribose) polymerase inhibitor during radiotherapy for rapidly progressing IDH-wildtype diffuse astrocytoma: a case report

2021 Case report CNS
Wang Z, Ren Y, Du F, Sun Y, et al. J Int Med Res. 2021 Aug;49(8):3000605211036847. Link [2021][Case report][CNS]

Dexamethasone Treatment Limits Efficacy of Radiation, but Does Not Interfere With Glioma Cell Death Induced by Tumor Treating Fields

2021 Basic research CNS
Linder B, Schiesl A, Voss M, Rödel F, et al. Front Oncol. 2021 Jul 30;11:715031. Link [2021][Basic research][CNS]

Case Report: End-Stage Recurrent Glioblastoma Treated With a New Noninvasive Non-Contact Oncomagnetic Device

2021 Case report CNS
Baskin DS, Sharpe MA, Nguyen L, Helekar SA. Front Oncol. 2021 Jul 22;11:708017. Link [2021][Case report][CNS]

Dielectrophoresis Structurization of PZT/PDMS Micro-Composite for Elastronic Function: Towards Dielectric and Piezoelectric Enhancement

2021 Others
D'Ambrogio G, Zahhaf O, Le MQ, Capsal JF, et al. Materials (Basel). 2021 Jul 21;14(15):4071. Link [2021][Others]

Tumor-Treating Fields for the treatment of glioblastoma: a systematic review and meta-analysis

2021 Systematic review / Meta-analysis CNS
Regev O, Merkin V, Blumenthal DT, Melamed I, et al. Neurooncol Pract. 2021 Apr 20;8(4):426-440. Link [2021][Systematic review / Meta-analysis][CNS]

Therapy of pancreatic cancer with alternating electric fields: Limitations of the method

2021 Basic research Pancreas
Pfeifer T, Bai L, Gladkich J, Gross W, et al. Bioelectrochemistry. 2021 Oct;141:107881. Link [2021][Basic research][Pancreas]

T Cells Retain Pivotal Antitumoral Functions under Tumor-Treating Electric Fields

2021 Basic research
Diamant G, Simchony Goldman H, Gasri Plotnitsky L, Roitman M, et al. J Immunol. 2021 Jul 15;207(2):709-719. Link [2021][Basic research]

Progress and prospect in tumor treating fields treatment of glioblastoma

2021 Review article CNS
Liu S, Shi W, Zhao Q, Zheng Z, et al. Biomed Pharmacother. 2021 Sep;141:111810. Link [2021][Review article][CNS]

Thymidine decreases the DNA damage and apoptosis caused by tumor-treating fields in cancer cell lines

2021 Basic research
Jeong H, Jo Y, Yoon M, Hong S. Genes Genomics. 2021 Sep;43(9):995-1001. Link [2021][Basic research]

Tumor-treating fields (TTFields)-based cocktail therapy: a novel blueprint for glioblastoma treatment

2021 Review article CNS
Wang M, Zhang C, Wang X, Yu H, et al. Am J Cancer Res. 2021 Apr 15;11(4):1069-1086. Link [2021][Review article][CNS]

Tumor-Treating Fields Therapy for Pediatric Brain Tumors

2021 Review article CNS Pediatric
Makimoto A, Nishikawa R, Terashima K, Kurihara J, et al. Neurol Int. 2021 Apr 8;13(2):151-165. Link [2021][Review article][CNS][Pediatric]

Brain-invasive meningiomas: molecular mechanisms and potential therapeutic options

2021 Review article CNS
Qin C, Huang M, Pan Y, Li Y, et al. Brain Tumor Pathol. 2021 Jul;38(3):156-172. Link [2021][Review article][CNS]

PTEN mutations predict benefit from tumor treating fields (TTFields) therapy in patients with recurrent glioblastoma

2021 Clinical research CNS
Dono A, Mitra S, Shah M, Takayasu T, et al. J Neurooncol. 2021 May;153(1):153-160. Link [2021][Clinical research][CNS]

Observations on the anti-glioma potential of electrical fields: is there a role for surgical neuromodulation?

2021 Review article CNS
Kumaria A. Br J Neurosurg. 2021 Feb 13:1-5. Link [2021][Review article][CNS]

Advances in radiotherapy and comprehensive treatment of high-grade glioma: immunotherapy and tumor-treating fields

2021 Review article CNS
Liu S, Zhao Q, Shi W, Zheng Z, et al. J Cancer. 2021 Jan 1;12(4):1094-1104. Link [2021][Review article][CNS]

Dosimetric impact of the positioning variation of tumor treating field electrodes in the PriCoTTF-phase I/II trial

2021 Clinical research CNS
Nour Y, Pöttgen C, Kebir S, Lazaridis L, et al. J Appl Clin Med Phys. 2021 Jan;22(1):242-250. Link [2021][Clinical research][CNS]

Tumor treating fields (TTFields) impairs aberrant glycolysis in glioblastoma as evaluated by [ 18 F]DASA-23, a non-invasive probe of pyruvate kinase M2 (PKM2) expression

2021 Basic research CNS
Patel CB, Beinat C, Xie Y, Chang E, et al. Neoplasia. 2021 Jan;23(1):58-67. Link [2021][Basic research][CNS]

Tumour treating fields therapy for glioblastoma: current advances and future directions

2021 Review article CNS
Rominiyi O, Vanderlinden A, Clenton SJ, Bridgewater C, et al. Br J Cancer. 2021 Feb;124(4):697-709. Link [2021][Review article][CNS]

Rapalink-1 Targets Glioblastoma Stem Cells and Acts Synergistically with Tumor Treating Fields to Reduce Resistance against Temozolomide

2020 Basic research CNS
Vargas-Toscano A, Nickel AC, Li G, Kamp MA, et al. Cancers (Basel). 2020 Dec 21;12(12):3859. Link [2020][Basic research][CNS]

Congress of neurological surgeons systematic review and evidence-based guidelines update on the role of emerging developments in the management of newly diagnosed glioblastoma

2020 Review article CNS
Farrell C, Shi W, Bodman A, Olson JJ. J Neurooncol. 2020 Nov;150(2):269-359. Link [2020][Review article][CNS]

Feasibility of Treating High Grade Gliomas in Children with Tumor-Treating Fields: A Case Series

2020 Case report CNS Pediatric
Crawford J, Saria MG, Dhall G, Margol A, et al. Cureus. 2020 Oct 5;12(10):e10804. Link [2020][Case report][CNS][Pediatric]

Sorafenib increases tumor treating fields-induced cell death in glioblastoma by inhibiting STAT3

2020 Basic research CNS
Kim JY, Jo Y, Oh HK, Kim EH. Am J Cancer Res. 2020 Oct 1;10(10):3475-3486. Link [2020][Basic research][CNS]

An overview of potential novel mechanisms of action underlying Tumor Treating Fields-induced cancer cell death and their clinical implications

2020 Review article CNS
Karanam NK, Story MD. Int J Radiat Biol. 2020 Oct 29:1-11. Link [2020][Review article][CNS]

Tumor Treating Fields (TTFields) Hinder Cancer Cell Motility through Regulation of Microtubule and Acting Dynamics

2020 Basic research
Voloshin T, Schneiderman RS, Volodin A, Shamir RR, et al. Cancers (Basel). 2020 Oct 17;12(10):3016. Link [2020][Basic research]

Tumor treating fields (TTF) treatment enhances radiation-induced apoptosis in pancreatic cancer cells

2020 Basic research Pancreas
Jo Y, Oh G, Gi Y, Sung H, et al. Int J Radiat Biol. 2020 Dec;96(12):1528-1533. Link [2020][Basic research][Pancreas]

Optimal treatment strategy for adult patients with newly diagnosed glioblastoma: a systematic review and network meta-analysis

2020 Systematic review / Meta-analysis CNS
Jin L, Guo S, Zhang X, Mo Y, et al. Neurosurg Rev. 2021 Aug;44(4):1943-1955. Link [2020][Systematic review / Meta-analysis][CNS]

Clinical Efficacy of Tumor Treating Fields for Newly Diagnosed Glioblastoma

2020 Clinical research CNS
Liu Y, Strawderman MS, Warren KT, Richardson M, et al. Anticancer Res. 2020 Oct;40(10):5801-5806. Link [2020][Clinical research][CNS]

Tumor-Treating Fields at EMBC 2019: A Roadmap to Developing a Framework for TTFields Dosimetry and Treatment Planning

2020 Review article CNS
Bomzon Z, Wenger C, Proescholdt M, Mohan S. 2020 Aug 6. In: Makarov SN, Noetscher GM, Nummenmaa A, editors. Brain and Human Body Modeling 2020: Computational Human Models Presented at EMBC 2019 and the BRAIN Initiative® 2019 Meeting [Internet]. Cham (CH): Springer; 2021 Link [2020][Review article][CNS]

Improving Tumor-Treating Fields with Skull Remodeling Surgery, Surgery Planning, and Treatment Evaluation with Finite Element Methods

2020 Review article CNS
Mikic N, Korshoej AR. 2020 Aug 6. In: Makarov SN, Noetscher GM, Nummenmaa A, editors. Brain and Human Body Modeling 2020: Computational Human Models Presented at EMBC 2019 and the BRAIN Initiative® 2019 Meeting [Internet]. Cham (CH): Springer; 2021. Link [2020][Review article][CNS]

A Thermal Study of Tumor-Treating Fields for Glioblastoma Therapy

2020 Review article CNS
Gentilal N, Salvador R, Miranda PC. 2020 Aug 6. In: Makarov SN, Noetscher GM, Nummenmaa A, editors. Brain and Human Body Modeling 2020: Computational Human Models Presented at EMBC 2019 and the BRAIN Initiative® 2019 Meeting [Internet]. Cham (CH): Springer; 2021. Link [2020][Review article][CNS]

How Do Tumor-Treating Fields Work?

2020 Review article CNS
Carlson KW, Tuszynski JA, Dokos S, Paudel N, et al. 2020 Aug 6. In: Makarov SN, Noetscher GM, Nummenmaa A, editors. Brain and Human Body Modeling 2020: Computational Human Models Presented at EMBC 2019 and the BRAIN Initiative® 2019 Meeting [Internet]. Cham (CH): Springer; 2021. Link [2020][Review article][CNS]

Physical approaches to treat glioblastoma

2020 Review article CNS
Latifyan S, de Micheli R, Hottinger AF. Curr Opin Oncol. 2020 Nov;32(6):640-649. Link [2020][Review article][CNS]

Heat transfer during TTFields treatment: Influence of the uncertainty of the electric and thermal parameters on the predicted temperature distribution

2020 Basic research CNS
Gentilal N, Miranda PC. Comput Methods Programs Biomed. 2020 Nov;196:105706. Link [2020][Basic research][CNS]

Evaluation of a tumor electric field treatment system in a rat model of glioma

2020 Basic research CNS
Wu H, Wang C, Liu J, Zhou D, et al. CNS Neurosci Ther. 2020 Nov;26(11):1168-1177. Link [2020][Basic research][CNS]

Tumor Treating Fields in the Management of Patients with Malignant Gliomas

2020 Review article CNS
Ghiaseddin AP, Shin D, Melnick K, Tran DD. Curr Treat Options Oncol. 2020 Jul 30;21(9):76. Link [2020][Review article][CNS]

Gene expression profiling of glioblastoma cell lines depending on TP53 status after tumor-treating fields (TTFields) treatment

2020 Basic research CNS
Lee YJ, Seo HW, Baek JH, Lim SH, et al. Sci Rep. 2020 Jul 23;10(1):12272. Link [2020][Basic research][CNS]

Tumor Treating Fields - Behind and Beyond Inhibiting the Cancer Cell Cycle

2020 Review article
Kissling C, Di Santo S. CNS Neurol Disord Drug Targets. 2020;19(8):599-610. Link [2020][Review article]

A systematic review of tumor treating fields therapy for high-grade gliomas

2020 Systematic review / Meta-analysis CNS
Shah PP, White T, Khalafallah AM, Romo CG, et al. J Neurooncol. 2020 Jul;148(3):433-443. Link [2020][Systematic review / Meta-analysis][CNS]

Global post-marketing safety surveillance of Tumor Treating Fields (TTFields) in patients with high-grade glioma in clinical practice

2020 Clinical research CNS
Shi W, Blumenthal DT, Oberheim Bush NA, Kebir S, et al. J Neurooncol. 2020 Jul;148(3):489-500. Link [2020][Clinical research][CNS]

A Theoretical Analysis of the Effects of Tumor-Treating Electric Fields on Single Cells

2020 Basic research CNS
Li X, Yang F, Gao B, Yu X, Rubinsky B. Bioelectromagnetics. 2020 Sep;41(6):438-446. Link [2020][Basic research][CNS]

Tumor treating fields for high-grade gliomas

2020 Review article CNS
Luo C, Xu S, Dai G, Xiao Z, et al. Biomed Pharmacother. 2020 Jul;127:110193. Link [2020][Review article][CNS]

The Value of Tumor Treating Fields in Glioblastoma

2020 Review article CNS
Zhang C, Du J, Xu W, Huang H, at al. J Korean Neurosurg Soc. 2020 Nov;63(6):681-688. Link [2020][Review article][CNS]

Combined radiotherapy and concurrent tumor treating fields (TTFields) for glioblastoma: Dosimetric consequences on non-coplanar IMRT as initial results from a phase I trial

2020 Clinical research CNS
Guberina N, Pöttgen C, Kebir S, Lazaridis L, et al. Radiat Oncol. 2020 Apr 19;15(1):83. Link [2020][Clinical research][CNS]

Impact of Peritumoral Edema During Tumor Treatment Field Therapy: A Computational Modelling Study

2020 Basic research CNS
Lang ST, Gan LS, McLennan C, Monchi O, et al. IEEE Trans Biomed Eng. 2020 Dec;67(12):3327-3338. Link [2020][Basic research][CNS]

Initial experience with scalp sparing radiation with concurrent temozolomide and tumor treatment fields (SPARE) for patients with newly diagnosed glioblastoma

2020 Clinical research CNS
Song A, Bar-Ad V, Martinez N, Glass J, et al. J Neurooncol. 2020 May;147(3):653-661. Link [2020][Clinical research][CNS]

Tumor treating fields in neuro-oncology: integration of alternating electric fields therapy into promising treatment strategies

2020 Review article CNS
Berger TR, Wong ET. Chin Clin Oncol. 2021 Aug;10(4):36. Link [2020][Review article][CNS]

Tumor-treating fields (TTFields) induce immunogenic cell death resulting in enhanced antitumor efficacy when combined with anti-PD-1 therapy

2020 Basic research
Voloshin T, Kaynan N, Davidi S, Porat Y, et al. Cancer Immunol Immunother. 2020 Jul;69(7):1191-1204. Link [2020][Basic research]

Barium Titanate Nanoparticles Sensitise Treatment-Resistant Breast Cancer Cells to the Antitumor Action of Tumour-Treating Fields

2020 Basic research Breast
Yoon YN, Lee DS, Park HJ, Kim JS. Sci Rep. 2020 Feb 13;10(1):2560. Link [2020][Basic research][Breast]

Tumor treating fields plus temozolomide for newly diagnosed glioblastoma: a sub-group analysis of Korean patients in the EF-14 phase 3 trial

2020 Clinical research CNS
Kim CY, Paek SH, Nam DH, Chang JH, et al. J Neurooncol. 2020 Feb;146(3):399-406. Link [2020][Clinical research][CNS]

Finite element analysis of Tumor Treating Fields in a patient with posterior fossa glioblastoma

2020 Case report CNS
Lok E, San P, Liang O, White V, et al. J Neurooncol. 2020 Mar;147(1):125-133. Link [2020][Case report][CNS]

A Theoretical Study on the Biophysical Mechanisms by Which Tumor Treating Fields Affect Tumor Cells During Mitosis

2020 Basic research
Li X, Yang F, Rubinsky B. IEEE Trans Biomed Eng. 2020 Sep;67(9):2594-2602. Link [2020][Basic research]

Complete radiological response following subtotal resection in three glioblastoma patients under treatment with Tumor Treating Fields

2020 Clinical research CNS
Kessler AF, Linsenmann T, Westermaier T, Wolber W, et al. Oncol Lett. 2020 Jan;19(1):557-561. Link [2020][Clinical research][CNS]

Tumor treating fields cause replication stress and interfere with DNA replication fork maintenance: Implications for cancer therapy

2020 Basic research
Karanam NK, Ding L, Aroumougame A, Story MD. Transl Res. 2020 Mar;217:33-46. Link [2020][Basic research]
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